Custom Synthesis

Global Chemsources represents a number of clients who offer production capacity and technological skills to carry out contract manufacturing of sophisticated organic chemical products on a custom basis. Included in our clients’ strengths are the following offerings:

Core Competency	Reagent / Process Strength
Acetylene Chemistry	Low temperature in liquid Ammonia
Acetylation	Acetic Anhydride / Acetic Acid
Azidation	Sodium Azide
Bromination	Bromine, Brominating Agent & Catalyst.
Chloro Sulphonation	Chloro Sulfonic Acid, Oleum at various temperature
Chlorination	With Reagents SO2Cl2, PCl3, PCl5, Chlorine with AlCl3
Cyclisation	With Light Paraffin Oil at 250^oC
Cyano Ethylation	With Acetonitrile at around 100^oC
Cyanation	Sodium Cyanide / HCN
Claisen Condensation	On Benzaldehyde
Diazotization	NaNO2 / Nitrosyl Sulphuric Acid / Isobutyl Nitrile.
Dicarboxylation	Dilute Caustic at High Temperature and Pressure.
Ethoxylation	Ethylene Oxide at temperature 40 to 100 Deg C
Ethylation	Bromide with Diethyl Sulphate.
Methylation	Methyl Chloride; Bromide with Dimethyl Sulphate
Chloromethylation	Bromide with Chloromethylation Compounds
Fractionation	Separation of various Isomers at wide temperature range.
Formylation	POCl3 and DMF
Grignard	With Magnesium Compounds
Hydrolysis	Caustic High Pressure
Lithiation	N-Butyl Lithium/ Lithium-di-isopropylamide / Lithium Metal
Nitration	Fuming HNO3, NaNO2 as well as HNO3 in Acetic Acid and Sulfuric Acid.
Oxidation	Hydrogen Peroxide/ Potassium Permanganese , Nitric Acid/ Sulphuric Acid.
PhoSgenation	Phosgene, Methyl Chloro Formate & Ethyl Chloroformate.
Resolution	R-(+)-PEA, D-Camphor Sulphonic Aicd, S-(+)-PEA
Reduction	Acidic with Fe & Zn Alkaline with Catalytic Catalytic Hydrogenation.
Stereo Specific Reaction	Sodium Borohydride. MDEB, Vitride.
Specialised condensation Reaction	STBO/ KTB/Sodium Ethoxide/ Sodium Metal.
Thio Alkylation	Mercaptide Solutions.
Thiolation	Hypexanthine / CS2